Referred to all over the world for its consciousness-altering properties, marijuana is reported to minimise involuntary muscle contractions experienced by some people with Multiple Sclerosis. Users of the renowned drug, that is derived from the flowering top of the hemp plant, cannabis sativa, have claimed that marijuana reportedly alleviated some of their Multiple Sclerosis symptoms.

Reports that marijuana decreased Multiple Sclerosis involuntary muscle spasms resulted in a small number of clinical trials carried out to determine if a promising drug or other medical treatment might actually help sufferers.

Initial clinical studies determined the function of tetrahydrocannabinol (THC), an active ingredient in the illegal drug in question, concerning the treatment methods of muscle spasms, tremor, and balance control in a restricted numbers of people afflicted with Multiple Sclerosis. However, the results of the studies are inconclusive, and clinical subjects noted an assortment of side effects.

However, these reports on the effect of THC to alleviate involuntary muscle spasms reveal contrasting results. While some people reported feeling totally relaxed and also became less prone to involuntary muscle spasms, the observable fact can not be specifically confirmed by objective testing. Results indicate the analgesic effects of marijuana lasted no more than three hours and in increased doses corollary reactions of weakness, thirst, lightheadedness, short-term memory loss, space and time distortions, and lack of motor control have been reported.

In a study of THC concerning 8 seriously disabled individuals with advanced tremor and lack of muscle co-ordination, two subjects reported significant improvement with tremor, which was verified by a doctor's examination however 3 reported improvement that could not be verified. All of the eight subjects that were given THC reported experiencing a high, whilst 2 reported sensations of uneasiness and restlessness.

A limited research on the effect of marijuana also revealed that the drug undermines motor coordination in posture control and equilibrium of people hurting from Multiple Sclerosis and even those that did not have Multiple Sclerosis, with all subjects reporting feelings of giddiness.

The National Academy of Science/Institute of Medicine released a report on March 17, 1999 that the medical uses of marijuana raised additional questions. Though the report did conclude that smoking marijuana does not have a direct part in the treatment of Multiple Sclerosis, the possibility exists that specific compounds derived from marijuana might possibly alleviate some Multiple Sclerosis related symptoms, particularly those related to involuntary muscle spasms. The report recommends that scientific and controlled research of the medicinal potential of cannabin compounds be undertaken combined with the safe development and dependable drug delivery tools.

Medical researchers have tested the capability of two derivatives from marijuana called cannabin and 3 synthetic cannabins to control unconscious muscle contractions and tremor, symptoms of the Multiple Sclerosis-like condition, in mice. The discoveries suggest that 4 different cannabins could temporarily relieve involuntary muscle spasms and/or tremor. Although the study recommended the derivatives of marijuana could be developed for human use, the initial obstacle will be to determine the right amount of these cannabins to make them a safe and workable treatment for those who have Multiple Sclerosis.

Using the results of studies accomplished to date as a place to start, the National Multiple Sclerosis Society's Medical Advisory Board states there are currently insufficient conclusive data to warrant the recommendation of marijuana or its derivatives as a treatment for people afflicted with Multiple Sclerosis and that extended use may cause considerable serious side effects.

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